Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis All domains of life feature diverse molecular clock machineries that synchronize physiological processes to diurnal environmental fluctuations. However, no mechanisms are…

Inflammasomes and the microbiota–partners in the preservation of mucosal homeostasis Inflammasomes are multiprotein complexes that serve as signaling platforms initiating innate immune responses. These structures are assembled upon a large…

The cross talk between microbiota and the immune system: metabolites take center stage The human meta-organism consists of more than 90% of microbial cells. The gastrointestinal tract harbors trillions of…

NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion Mucus production by goblet cells of the large intestine serves as a crucial antimicrobial protective mechanism at…

The interplay between the innate immune system and the microbiota The human gastrointestinal tract harbors one of the highest densities of microorganisms on earth, called the microbiota. In fact, the…